Appbp2 | amyloid beta precursor protein binding protein 2

GeneMGI:1914134Synonyms: PAT1, 1300003O07Rik

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Pigmentation Integument Growth/size/body region Behavior/neurological Mortality/aging Craniofacial

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal vocalization	1 supporting dataset	Appbp2^em1(IMPC)J	heterozygote	Early adult	2.42x10^-10
abnormal coat/hair pigmentation	1 supporting dataset	Appbp2^em1(IMPC)J	heterozygote	Early adult	4.2x10^-12
abnormal head morphology	1 supporting dataset	Appbp2^em1(IMPC)J	heterozygote	Early adult	4.12x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Appbp2^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal snout morphology	1 supporting dataset	Appbp2^em1(IMPC)J	heterozygote	Early adult	8.07x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Appbp2.

Associated images

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Histopathology

There is no histopathology data found for Appbp2.

IMPC related publications

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External links

No external links available for Appbp2.

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*Appbp2^em1(IMPC)J*	Intra-exon deletion	‌	mouse
*Appbp2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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