Swt1 | SWT1 RNA endoribonuclease homolog (S. cerevisiae)

GeneMGI:1914125Synonyms: 1200016B10Rik

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount2 supporting datasetsSwt1em1(IMPC)JhomozygoteEarly adult1.11x10-11 
decreased lean body mass2 supporting datasetsSwt1em1(IMPC)JhomozygoteEarly adult8.1x10-9 
impaired glucose tolerance1 supporting datasetSwt1em1(IMPC)JhomozygoteEarly adult3.23x10-5 
decreased bone mineral content1 supporting datasetSwt1em1(IMPC)JhomozygoteEarly adult1.49x10-6 
increased leukocyte cell number1 supporting datasetSwt1em1(IMPC)JhomozygoteEarly adult2.54x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Swt1em1(IMPC)JExon Deletionmouse

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