Ncbp3 | nuclear cap binding subunit 3

GeneMGI:1914124Synonyms: 1200014J11Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Cardiovascular system Mortality/aging

13 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

decreased lean body mass2 supporting datasetsNcbp3tm1b(EUCOMM)WtsiheterozygoteEarly adult2.04x10-5 
enlarged heart1 supporting datasetNcbp3tm1b(EUCOMM)WtsiheterozygoteEarly adultN/A * 
increased total body fat amount1 supporting datasetNcbp3tm1b(EUCOMM)WtsiheterozygoteEarly adult5.47x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetNcbp3tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ncbp3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ncbp3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Ncbp3tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ncbp3tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
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