Mfsd1 | major facilitator superfamily domain containing 1

GeneMGI:1914118Synonyms: 1200003O06Rik

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Skeleton Mortality/aging

11 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:26Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



enlarged spleen	2 supporting datasets	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
thrombocytopenia	1 supporting dataset	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	3.38x10^-9
small testis	1 supporting dataset	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal sternum morphology	1 supporting dataset	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased neutrophil cell number	1 supporting dataset	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	3.3x10^-12
preweaning lethality, incomplete penetrance	2 supporting datasets	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased leukocyte cell number	1 supporting dataset	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	2.45x10^-7
increased circulating aspartate transaminase level	1 supporting dataset	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	3.61x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Mfsd1^em1(IMPC)Tcp	homozygote	Early adult	0

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Mfsd1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Mfsd1.

IMPC related publications

Loading...

External links

No external links available for Mfsd1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Mfsd1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Mfsd1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mfsd1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes