Lztr1 | leucine-zipper-like transcriptional regulator, 1

GeneMGI:1914113Synonyms: 1200003E21Rik, TCFL2

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Hematopoietic system Skeleton Craniofacial Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

7Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal snout morphology	1 supporting dataset	Lztr1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	5.59x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Lztr1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal cranium morphology	1 supporting dataset	Lztr1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.4x10^-5
increased red blood cell distribution width	1 supporting dataset	Lztr1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.73x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lztr1.

Associated images

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Histopathology

There is no histopathology data found for Lztr1.

IMPC related publications

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External links

No external links available for Lztr1.

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*Lztr1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Lztr1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

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