Mcub | mitochondrial calcium uniporter dominant negative beta subunit

GeneMGI:1914065Synonyms: Ccdc109b, 9030408N13Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Integument Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



impaired righting response	1 supporting dataset	Mcub^{tm1b(KOMP)Mbp}	homozygote	Early adult	4.47x10^-6
absent vibrissae	1 supporting dataset	Mcub^{tm1b(KOMP)Mbp}	homozygote	Early adult	5.24x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mcub.

Associated images

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Histopathology

There is no histopathology data found for Mcub.

IMPC related publications

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External links

No external links available for Mcub.

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*Mcub^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mcub^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mcub^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mcub^{tm1c(KOMP)Mbp}*	Wild type floxed exon (post-Flp)	‌	mouse
*Mcub^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Mcub^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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