Grtp1 | GH regulated TBC protein 1

GeneMGI:1914040Synonyms: 5430401C05Rik, Tbc1d6

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Vision/eye

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alanine transaminase level	1 supporting dataset	Grtp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.22x10^-8
small seminal vesicle	1 supporting dataset	Grtp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased circulating aspartate transaminase level	1 supporting dataset	Grtp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.57x10^-6
microphthalmia	1 supporting dataset	Grtp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Grtp1.

Associated images

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Histopathology

There is no histopathology data found for Grtp1.

IMPC related publications

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External links

No external links available for Grtp1.

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*Grtp1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Grtp1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Grtp1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Grtp1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Grtp1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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