Alg14 | asparagine-linked glycosylation 14

GeneMGI:1914039Synonyms: 5430428G01Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

18 No significant impact

4 Not tested

Gene metrics:3Significant phenotypes
4Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues

Phenotypes

increased cornea thickness1 supporting datasetAlg14tm2b(EUCOMM)HmguheterozygoteEarly adult3.81x10-6 
preweaning lethality, complete penetrance3 supporting datasetsAlg14tm2b(EUCOMM)HmguhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetAlg14tm2b(EUCOMM)HmguhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Alg14tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Alg14tm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Alg14tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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