4933434E20Rik | RIKEN cDNA 4933434E20 gene

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating HDL cholesterol level1 supporting dataset4933434E20Riktm1a(EUCOMM)WtsiheterozygoteEarly adult5.29x10-7 
decreased circulating fructosamine level1 supporting dataset4933434E20Riktm1a(EUCOMM)WtsiheterozygoteEarly adult4.74x10-7 
increased circulating alanine transaminase level1 supporting dataset4933434E20Riktm1a(EUCOMM)WtsiheterozygoteEarly adult6.74x10-5 
decreased circulating cholesterol level1 supporting dataset4933434E20Riktm1a(EUCOMM)WtsiheterozygoteEarly adult5.07x10-6 
decreased circulating serum albumin level1 supporting dataset4933434E20Riktm1a(EUCOMM)WtsiheterozygoteEarly adult2.43x10-6 
preweaning lethality, complete penetrance1 supporting dataset4933434E20Riktm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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4933434E20Riktm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
4933434E20Riktm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
4933434E20Riktm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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