Zfp474 | zinc finger protein 474

GeneMGI:1914008Synonyms: 4933409D10Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Limbs/digits/tail Hematopoietic system Cardiovascular system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged heart	1 supporting dataset	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.4x10^-5
abnormal skin morphology	2 supporting datasets	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased eosinophil cell number	2 supporting datasets	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.83x10^-11
small testis	1 supporting dataset	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased neutrophil cell number	2 supporting datasets	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.39x10^-7
abnormal testis morphology	1 supporting dataset	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal digit morphology	1 supporting dataset	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.83x10^-14
abnormal heart morphology	1 supporting dataset	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased lymphocyte cell number	1 supporting dataset	Zfp474^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.54x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zfp474.

Associated images

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Histopathology

There is no histopathology data found for Zfp474.

IMPC related publications

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External links

No external links available for Zfp474.

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*Zfp474^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Zfp474^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Zfp474^{tm279483(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Zfp474^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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