Chmp3 | charged multivesicular body protein 3
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Vision/eye Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues
impaired glucose tolerance | 1 supporting dataset | Chmp3tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.21x10-5 | ||
decreased prepulse inhibition | 1 supporting dataset | Chmp3tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.32x10-7 | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Chmp3tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Chmp3tm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
abnormal cornea morphology | 1 supporting dataset | Chmp3tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.71x10-6 |
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External links
No external links available for Chmp3.
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Chmp3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Chmp3tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Chmp3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |