Eef1d | eukaryotic translation elongation factor 1 delta

GeneMGI:1913906Synonyms: 1700026P12Rik, 5730529A16Rik

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Embryo Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system Cardiovascular system Mortality/aging Renal/urinary system

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



edema	1 supporting dataset	Eef1d^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
eye hemorrhage	1 supporting dataset	Eef1d^em1(IMPC)Mbp	heterozygote	Early adult	8.85x10^-5
edema	1 supporting dataset	Eef1d^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal auditory brainstem response	1 supporting dataset	Eef1d^em1(IMPC)Mbp	heterozygote	Early adult	5.64x10^-5
abnormal skin morphology	1 supporting dataset	Eef1d^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Eef1d^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal retina morphology	1 supporting dataset	Eef1d^em1(IMPC)Mbp	heterozygote	Early adult	5.89x10^-6
abnormal placenta vasculature	1 supporting dataset	Eef1d^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Eef1d^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Eef1d^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Eef1d.

Associated images

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Histopathology

There is no histopathology data found for Eef1d.

IMPC related publications

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External links

No external links available for Eef1d.

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*Eef1d^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Eef1d^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Eef1d^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Eef1d^{tm450623(L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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