Rpe | ribulose-5-phosphate-3-epimerase

GeneMGI:1913896Synonyms: 5730518J08Rik, 2810429B02Rik

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging Renal/urinary system

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



enlarged spleen	2 supporting datasets	Rpe^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Rpe^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Rpe^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Rpe^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
small heart	1 supporting dataset	Rpe^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Rpe^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased freezing behavior	1 supporting dataset	Rpe^em1(IMPC)Mbp	heterozygote	Early adult	2.48x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Rpe^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal kidney morphology	1 supporting dataset	Rpe^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
enlarged kidney	1 supporting dataset	Rpe^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rpe.

Associated images

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Histopathology

There is no histopathology data found for Rpe.

IMPC related publications

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External links

No external links available for Rpe.

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*Rpe^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Rpe^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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