Pspc1 | paraspeckle protein 1

GeneMGI:1913895Synonyms: 5730470C09Rik, PSP1

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Immune system Growth/size/body region Hematopoietic system Behavior/neurological

14 No significant impact

5 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetPspc1em1(IMPC)MbphomozygoteEarly adult7.06x10-5 
increased thigmotaxis2 supporting datasetsPspc1em1(IMPC)MbphomozygoteEarly adult5.86x10-5 
abnormal spleen morphology2 supporting datasetsPspc1em1(IMPC)MbphomozygoteEarly adultN/A * 
male infertility1 supporting datasetPspc1em1(IMPC)MbphomozygoteEarly adultN/A * 
small spleen1 supporting datasetPspc1em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased exploration in new environment1 supporting datasetPspc1em1(IMPC)MbphomozygoteEarly adult2.9x10-5 
enlarged spleen1 supporting datasetPspc1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pspc1em1(IMPC)MbpExon Deletionmouse
Pspc1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Pspc1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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