Nsa2 | NSA2 ribosome biogenesis homolog

GeneMGI:1913883Synonyms: 5730427N09Rik, LNR42, +2 more

Physiological systems

22 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Mortality/aging

18 No significant impact

2 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsNsa2em1(IMPC)MbphomozygoteEarly adultN/A * 
embryonic growth retardation1 supporting datasetNsa2em1(IMPC)MbpheterozygoteE15.5N/A * 
edema1 supporting datasetNsa2em1(IMPC)MbpheterozygoteE15.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetNsa2em1(IMPC)MbphomozygoteE9.5N/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetNsa2em1(IMPC)MbphomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nsa2em1(IMPC)MbpExon Deletionmouse
Nsa2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nsa2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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