Ubr7 | ubiquitin protein ligase E3 component n-recognin 7 (putative)

GeneMGI:1913872Synonyms: 5730410I19Rik

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	7.45x10^-5
increased startle reflex	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	1.39x10^-10
decreased hemoglobin content	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	2.28x10^-6
increased lymphocyte cell number	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	1.21x10^-6
short tibia	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	5.4x10^-6
abnormal retina vasculature morphology	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	1.74x10^-5
shortened RR interval	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	5.91x10^-9
decreased mean corpuscular hemoglobin	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	6.93x10^-5
increased leukocyte cell number	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	3.14x10^-6
decreased circulating serum albumin level	1 supporting dataset	Ubr7^em1(IMPC)Tcp	homozygote	Early adult	6.48x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ubr7.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ubr7.

IMPC related publications

Loading...

External links

No external links available for Ubr7.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ubr7^em1(IMPC)Tcp*	Insertion, Intragenic deletion	‌	mouse
*Ubr7^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ubr7^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ubr7^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes