Exosc1 | exosome component 1

GeneMGI:1913833Synonyms: 2610104C07Rik, 2610035C18Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Integument Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetExosc1em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal coat/ hair morphology1 supporting datasetExosc1em1(IMPC)JheterozygoteEarly adult9.35x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Exosc1em1(IMPC)JExon Deletionmouse
Exosc1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Exosc1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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