Xpo5 | exportin 5

GeneMGI:1913789Synonyms: Exp5, 2700038C24Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Embryo Growth/size/body region Nervous system Vision/eye Hematopoietic system Cardiovascular system Mortality/aging

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal ovary morphology	1 supporting dataset	Xpo5^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
enlarged ovary	1 supporting dataset	Xpo5^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
spina bifida	1 supporting dataset	Xpo5^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal spleen morphology	1 supporting dataset	Xpo5^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Xpo5^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Xpo5^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Xpo5^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
hemorrhage	1 supporting dataset	Xpo5^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Xpo5^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Xpo5^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Xpo5.

Associated images

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Histopathology

There is no histopathology data found for Xpo5.

IMPC related publications

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External links

No external links available for Xpo5.

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*Xpo5^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Xpo5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Xpo5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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