Pgpep1 | pyroglutamyl-peptidase I

GeneMGI:1913772Synonyms: Pcp, 2810003H13Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating calcium level	1 supporting dataset	Pgpep1^em1(IMPC)J	homozygote	Early adult	6.34x10^-7
increased startle reflex	1 supporting dataset	Pgpep1^em1(IMPC)J	homozygote	Early adult	3.2x10^-13
decreased prepulse inhibition	1 supporting dataset	Pgpep1^em1(IMPC)J	homozygote	Early adult	1.96x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pgpep1.

Associated images

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Histopathology

There is no histopathology data found for Pgpep1.

IMPC related publications

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External links

No external links available for Pgpep1.

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*Pgpep1^em1(IMPC)J*	Whole-gene deletion	‌	mouse
*Pgpep1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pgpep1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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