Lamtor1 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1

GeneMGI:1913758Synonyms: 2400001E08Rik, p18

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Growth/size/body region Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal testis morphology	1 supporting dataset	Lamtor1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Lamtor1^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
enlarged testis	1 supporting dataset	Lamtor1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Lamtor1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal ovary morphology	1 supporting dataset	Lamtor1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
enlarged ovary	1 supporting dataset	Lamtor1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Lamtor1^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Lamtor1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Lamtor1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lamtor1.

Associated images

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Histopathology

There is no histopathology data found for Lamtor1.

IMPC related publications

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External links

No external links available for Lamtor1.

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*Lamtor1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Lamtor1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Lamtor1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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