Mrpl51 | mitochondrial ribosomal protein L51

GeneMGI:1913743Synonyms: HSPC241, 2610511M02Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging Renal/urinary system

17 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues

Phenotypes

increased urine magnesium level1 supporting datasetMrpl51tm1.1(KOMP)VlcgheterozygoteEarly adult7.56x10-5 
embryonic lethality prior to organogenesis1 supporting datasetMrpl51tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetMrpl51tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetMrpl51tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
decreased circulating glucose level1 supporting datasetMrpl51tm1.1(KOMP)VlcgheterozygoteEarly adult3.65x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mrpl51tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Mrpl51tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Mrpl51tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Mrpl51tm456517(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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