Taf12 | TATA-box binding protein associated factor 12

GeneMGI:1913714Synonyms: Taf2J, 2810422D08Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Embryo Nervous system Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal hindbrain development1 supporting datasetTaf12em1(IMPC)MbpheterozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsTaf12em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal neural tube morphology1 supporting datasetTaf12em1(IMPC)MbpheterozygoteE9.5N/A * 
abnormal neural tube closure1 supporting datasetTaf12em1(IMPC)MbpheterozygoteE9.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetTaf12em1(IMPC)MbphomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Taf12em1(IMPC)MbpIntra-exon deletionmouse
Taf12tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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