Tnfaip8l1 | tumor necrosis factor, alpha-induced protein 8-like 1

GeneMGI:1913693Synonyms: 2600017J23Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



small spleen	1 supporting dataset	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
small liver	1 supporting dataset	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	2 supporting datasets	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged heart	1 supporting dataset	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged liver	1 supporting dataset	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Tnfaip8l1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tnfaip8l1.

Associated images

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Histopathology

There is no histopathology data found for Tnfaip8l1.

IMPC related publications

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External links

No external links available for Tnfaip8l1.

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*Tnfaip8l1^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse
*Tnfaip8l1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Tnfaip8l1^{tm96610(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Tnfaip8l1^{tm96610(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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