Spc25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)

GeneMGI:1913692Synonyms: Spbc25, 2610205L13Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Spc25^em1(IMPC)J	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Spc25^em1(IMPC)J	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Spc25.

Associated images

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Histopathology

There is no histopathology data found for Spc25.

IMPC related publications

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External links

No external links available for Spc25.

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*Spc25^em1(IMPC)J*	Whole-gene deletion	‌	mouse
*Spc25^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Spc25^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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