Cyb5b | cytochrome b5 type B

GeneMGI:1913677Synonyms: 1810044O22Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

64Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



no spontaneous movement	1 supporting dataset	Cyb5b^{tm1b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Cyb5b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
no spontaneous movement	1 supporting dataset	Cyb5b^{tm1b(EUCOMM)Hmgu}	heterozygote	E18.5	N/A ^*
increased circulating alkaline phosphatase level	1 supporting dataset	Cyb5b^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.5x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cyb5b.

Associated images

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Histopathology

There is no histopathology data found for Cyb5b.

IMPC related publications

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External links

No external links available for Cyb5b.

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*Cyb5b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cyb5b^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cyb5b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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