Nosip | nitric oxide synthase interacting protein
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Hematopoietic system Mortality/aging Cardiovascular system
13 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Nosipem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Nosipem1(IMPC)Tcp | heterozygote | Early adult | 3.51x10-7 | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Nosipem1(IMPC)Tcp | heterozygote | Early adult | 3.51x10-5 | ||
| edema | 1 supporting dataset | Nosipem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| abnormal lens morphology | 1 supporting dataset | Nosipem1(IMPC)Tcp | heterozygote | Early adult | 8.05x10-5 | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Nosipem1(IMPC)Tcp | heterozygote | Early adult | 1.97x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Nosipem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| thrombocytosis | 1 supporting dataset | Nosipem1(IMPC)Tcp | heterozygote | Early adult | 5.69x10-5 |
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External links
No external links available for Nosip.
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| Nosipem1(IMPC)Tcp | Exon Deletion | | mouse |
| Nosiptm88115(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |