Adprm | ADP-ribose/CDP-alcohol diphosphatase, manganese dependent

GeneMGI:1913608Synonyms: 2310004I24Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal behavior1 supporting datasetAdprmtm1b(EUCOMM)HmguhomozygoteEarly adult8.34x10-7 
decreased thigmotaxis2 supporting datasetsAdprmtm1b(EUCOMM)HmguhomozygoteEarly adult8.33x10-7 
decreased anxiety-related response1 supporting datasetAdprmtm1b(EUCOMM)HmguhomozygoteEarly adult5.34x10-6 
decreased startle reflex1 supporting datasetAdprmtm1b(EUCOMM)HmguhomozygoteEarly adult3.13x10-6 
decreased locomotor activity1 supporting datasetAdprmtm1b(EUCOMM)HmguhomozygoteEarly adult6.54x10-10 
decreased respiratory quotient1 supporting datasetAdprmtm1b(EUCOMM)HmguhomozygoteEarly adult7.11x10-5 
hyperactivity2 supporting datasetsAdprmtm1b(EUCOMM)HmguhomozygoteEarly adult5.19x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Adprmtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Adprmtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Adprmtm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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