Rpl7l1 | ribosomal protein L7-like 1

GeneMGI:1913479Synonyms: 1500016H10Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Vision/eye Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetRpl7l1tm2b(EUCOMM)HmguhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsRpl7l1tm2b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal eye anterior chamber depth2 supporting datasetsRpl7l1tm2b(EUCOMM)HmguheterozygoteEarly adult1.87x10-23 
abnormal coat/ hair morphology1 supporting datasetRpl7l1tm2b(EUCOMM)HmguheterozygoteEarly adult4.07x10-6 
abnormal coat appearance1 supporting datasetRpl7l1tm2b(EUCOMM)HmguheterozygoteEarly adult4.2x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rpl7l1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rpl7l1tm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Rpl7l1tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Rpl7l1tm84605(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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