Sec61b | SEC61 translocon subunit beta

GeneMGI:1913462Synonyms: 1190006C12Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Behavior/neurological

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	2 supporting datasets	Sec61b^em1(IMPC)Mbp	homozygote	Early adult	5.48x10^-7
abnormal ovary morphology	1 supporting dataset	Sec61b^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased circulating insulin level	1 supporting dataset	Sec61b^em1(IMPC)Mbp	homozygote	Early adult	5.89x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sec61b.

Associated images

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Histopathology

There is no histopathology data found for Sec61b.

IMPC related publications

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External links

No external links available for Sec61b.

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*Sec61b^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Sec61b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell

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