Ier3ip1 | immediate early response 3 interacting protein 1
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging
15 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Ier3ip1em1(IMPC)J | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ier3ip1em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| abnormal vocalization | 1 supporting dataset | Ier3ip1em1(IMPC)J | heterozygote | Early adult | 1.69x10-6 | ||
| decreased locomotor activity | 1 supporting dataset | Ier3ip1em1(IMPC)J | heterozygote | Early adult | 9.37x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Ier3ip1em1(IMPC)J | heterozygote | Early adult | 3.3x10-9 |
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External links
No external links available for Ier3ip1.
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| Ier3ip1em1(IMPC)J | Exon Deletion | | mouse |
| Ier3ip1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Ier3ip1tm436543(L1L2_GT1_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |