S100a14 | S100 calcium binding protein A14

GeneMGI:1913416Synonyms: 1110013O05Rik, S100a15

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Mortality/aging

16 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
50Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance2 supporting datasetsS100a14tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetS100a14tm1b(EUCOMM)HmguheterozygoteEarly adult3.72x10-5 
preweaning lethality, complete penetrance1 supporting datasetS100a14tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased circulating aspartate transaminase level1 supporting datasetS100a14tm1b(EUCOMM)HmguheterozygoteEarly adult5.57x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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S100a14tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
S100a14tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
S100a14tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
S100a14tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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