Bud23 | BUD23, rRNA methyltransferase and ribosome maturation factor

GeneMGI:1913388Synonyms: Wbscr22, 1110003N24Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetBud23em2(IMPC)HhomozygoteE9.5N/A * 
decreased circulating glucose level1 supporting datasetBud23em2(IMPC)HheterozygoteEarly adult1.05x10-5 
preweaning lethality, complete penetrance1 supporting datasetBud23em2(IMPC)HhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bud23em1(IMPC)HExon Deletionmouse
Bud23em2(IMPC)HExon Deletionmouse
Bud23em3(IMPC)HExon Deletionmouse
Bud23tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Bud23tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Bud23tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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