Chchd1 | coiled-coil-helix-coiled-coil-helix domain containing 1

GeneMGI:1913371Synonyms: 1110001O19Rik, 2400010G13Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Integument Embryo Growth/size/body region Nervous system Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

29Embryo tissues

Phenotypes

Phy. System:

Life Stage:



pale yolk sac	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
pallor	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal forebrain development	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal hindbrain development	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal midbrain development	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	2 supporting datasets	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal neural tube closure	1 supporting dataset	Chchd1^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Chchd1.

Associated images

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Histopathology

There is no histopathology data found for Chchd1.

IMPC related publications

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External links

No external links available for Chchd1.

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*Chchd1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Chchd1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Chchd1^{tm214240(L1L2_Bact_P)}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector

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