Lamtor4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

GeneMGI:1913346Synonyms: 0910001L09Rik

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Endocrine/exocrine gland Embryo Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Mortality/aging

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased locomotor activity	2 supporting datasets	Lamtor4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	2.38x10^-5
embryonic lethality prior to tooth bud stage	1 supporting dataset	Lamtor4^{em1(IMPC)Ccpcz}	homozygote	E12.5	N/A ^*
enlarged thyroid gland	1 supporting dataset	Lamtor4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal thyroid gland morphology	1 supporting dataset	Lamtor4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Lamtor4^{em1(IMPC)Ccpcz}	homozygote	E9.5	N/A ^*
hyperactivity	1 supporting dataset	Lamtor4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	4.97x10^-5
decreased thigmotaxis	2 supporting datasets	Lamtor4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	3.49x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Lamtor4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal rib morphology	1 supporting dataset	Lamtor4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.38x10^-5
decreased mean platelet volume	1 supporting dataset	Lamtor4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	9.26x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Lamtor4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Lamtor4.

IMPC related publications

Loading...

External links

No external links available for Lamtor4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Lamtor4^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Lamtor4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Lamtor4^{tm213120(L1L2_Bact_P)}*		‌	targeting vector

My Genes