Sdhc | succinate dehydrogenase complex, subunit C, integral membrane protein
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Growth/size/body region Hematopoietic system Mortality/aging
18 No significant impact
3 Not tested
Data collections
Gene metrics:5Significant phenotypes
7Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Sdhctm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| thrombocytosis | 1 supporting dataset | Sdhctm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.07x10-6 | ||
| increased body weight | 1 supporting dataset | Sdhctm1a(EUCOMM)Wtsi | heterozygote | Early adult | 5.11x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Sdhctm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Sdhc.
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| Sdhctm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Sdhctm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Sdhctm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |