Emc6 | ER membrane protein complex subunit 6

GeneMGI:1913298Synonyms: 0610009E20Rik, 0610025L18Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
29Embryo tissues

Phenotypes

increased hematocrit1 supporting datasetEmc6tm1.1(KOMP)VlcgheterozygoteEarly adult9.17x10-5 
embryonic lethality prior to organogenesis1 supporting datasetEmc6tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
preweaning lethality, complete penetrance2 supporting datasetsEmc6tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetEmc6tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Emc6tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Emc6tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Emc6tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Emc6tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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