Sostdc1 | sclerostin domain containing 1

GeneMGI:1913292Synonyms: ectodin, Sostl, +2 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

19 No significant impact

3 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

persistence of hyaloid vascular system1 supporting datasetSostdc1tm1.1(KOMP)VlcghomozygoteEarly adult1.76x10-5 
preweaning lethality, incomplete penetrance3 supporting datasetsSostdc1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sostdc1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Sostdc1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Sostdc1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Sostdc1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Sostdc1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Sostdc1tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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