Crbn | cereblon
Physiological systems
22 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Digestive/alimentary Nervous system Vision/eye
19 No significant impact
2 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| decreased prepulse inhibition | 3 supporting datasets | Crbntm1b(KOMP)Wtsi | homozygote | Early adult | 1.11x10-7 | ||
| abnormal cecum morphology | 1 supporting dataset | Crbntm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| absent optic nerve | 1 supporting dataset | Crbntm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Crbntm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Crbn.
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| Crbntm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Crbntm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Crbntm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Crbntm1e(KOMP)Mbp | Targeted, non-conditional allele | | es cell |
| Crbntm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell mouse |