Tmem45a | transmembrane protein 45a

GeneMGI:1913122Synonyms: C630002M10Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological

14 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small testis1 supporting datasetTmem45aem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased grip strength4 supporting datasetsTmem45aem1(IMPC)MbphomozygoteEarly adult2.95x10-14 
abnormal testis morphology1 supporting datasetTmem45aem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsTmem45aem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetTmem45aem1(IMPC)MbphomozygoteEarly adultN/A * 
small spleen1 supporting datasetTmem45aem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmem45aem1(IMPC)MbpExon Deletionmouse
Tmem45atm380408(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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