Il1rl2 | interleukin 1 receptor-like 2

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity1 supporting datasetIl1rl2em1(IMPC)MbphomozygoteEarly adult1.02x10-8 
decreased thigmotaxis2 supporting datasetsIl1rl2em1(IMPC)MbphomozygoteEarly adult5.51x10-5 
abnormal eye morphology2 supporting datasetsIl1rl2em1(IMPC)MbphomozygoteEarly adultN/A * 
hyperactivity1 supporting datasetIl1rl2em1(IMPC)MbphomozygoteEarly adult2.12x10-5 
abnormal behavior1 supporting datasetIl1rl2em1(IMPC)MbphomozygoteEarly adult7.44x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il1rl2em1(IMPC)MbpExon Deletionmouse
Il1rl2tm384302(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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