Hdac7 | histone deacetylase 7

GeneMGI:1891835Synonyms: 5830434K02Rik, Hdac7a

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

64Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal coat/hair pigmentation	3 supporting datasets	Hdac7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.46x10^-10
increased circulating alkaline phosphatase level	1 supporting dataset	Hdac7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.43x10^-6
embryonic lethality prior to tooth bud stage	1 supporting dataset	Hdac7^{tm1b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hdac7.

Associated images

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Histopathology

There is no histopathology data found for Hdac7.

IMPC related publications

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External links

No external links available for Hdac7.

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*Hdac7^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hdac7^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hdac7^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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