Ppp4c | protein phosphatase 4, catalytic subunit

GeneMGI:1891763Synonyms: PPX, 1110002D08Rik

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Behavior/neurological Cardiovascular system

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating bilirubin level1 supporting datasetPpp4cem1(IMPC)IcsheterozygoteEarly adult2.4x10-5 
abnormal contextual conditioning behavior1 supporting datasetPpp4cem1(IMPC)IcsheterozygoteEarly adult9.12x10-5 
increased heart weight1 supporting datasetPpp4cem1(IMPC)IcsheterozygoteEarly adult1.26x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ppp4cem1(IMPC)IcsDeletionmouse
Ppp4ctm295624(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Ppp4ctm295624(L1L2_gt0_Del_LacZ)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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