Dctn5 | dynactin 5

GeneMGI:1891689Synonyms: b2b315Clo, 4930427E12Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



cataract	1 supporting dataset	Dctn5^{tm2a(KOMP)Wtsi}	heterozygote	Early adult	9.83x10^-6
abnormal behavior	1 supporting dataset	Dctn5^{tm2a(KOMP)Wtsi}	heterozygote	Early adult	6.89x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Dctn5^{tm2a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal lens morphology	1 supporting dataset	Dctn5^{tm2a(KOMP)Wtsi}	heterozygote	Early adult	1.18x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dctn5.

Associated images

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Histopathology

There is no histopathology data found for Dctn5.

IMPC related publications

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External links

No external links available for Dctn5.

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*Dctn5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Dctn5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Dctn5^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Dctn5^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Dctn5^{tm41679(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes