Kirrel1 | kirre like nephrin family adhesion molecule 1

GeneMGI:1891396Synonyms: Kirrel1, Kirrel, +2 more

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Embryo Growth/size/body region Vision/eye Cardiovascular system Mortality/aging

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal retina vasculature morphology	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	heterozygote	Early adult	1.34x10^-5
microphthalmia	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
cataract	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	heterozygote	Early adult	6.42x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	heterozygote	Early adult	8.6x10^-6
abnormal placenta vasculature	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	heterozygote	Early adult	8.92x10^-5
abnormal placenta morphology	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
eye hemorrhage	1 supporting dataset	Kirrel1^em1(IMPC)Mbp	heterozygote	Early adult	1.32x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kirrel1.

Associated images

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Histopathology

There is no histopathology data found for Kirrel1.

IMPC related publications

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External links

No external links available for Kirrel1.

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*Kirrel1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Kirrel1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Kirrel1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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