Fgf20 | fibroblast growth factor 20

Physiological systems

22 / 24 physiological systems tested

17 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Hematopoietic system Cardiovascular system Craniofacial Renal/urinary system Homeostasis/metabolism Limbs/digits/tail Nervous system Vision/eye Liver/biliary system Behavior/neurological Skeleton

5 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:36Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged spleen	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal autopod morphology	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.5x10^-5
fusion of vertebral arches	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.6x10^-6
small kidney	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal hindlimb morphology	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.96x10^-5
abnormal nail morphology	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.5x10^-5
abnormal startle reflex	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.02x10^-17
decreased startle reflex	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.47x10^-5
enlarged heart	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
vertebral fusion	1 supporting dataset	Fgf20^{em1(IMPC)Ccpcz}	homozygote	Early adult	7.24x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fgf20.

Associated images

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Histopathology

There is no histopathology data found for Fgf20.

IMPC related publications

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External links

No external links available for Fgf20.

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*Fgf20^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Fgf20^{tm95301(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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