Zfp423 | zinc finger protein 423

GeneMGI:1891217Synonyms: Ebfaz, Zfp104, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

persistence of hyaloid vascular system1 supporting datasetZfp423em1(IMPC)JheterozygoteEarly adult2.01x10-5 
preweaning lethality, complete penetrance1 supporting datasetZfp423em1(IMPC)JhomozygoteEarly adultN/A * 
increased circulating alkaline phosphatase level1 supporting datasetZfp423em1(IMPC)JheterozygoteEarly adult1.04x10-5 
decreased locomotor activity1 supporting datasetZfp423em1(IMPC)JheterozygoteEarly adult7.56x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp423em1(IMPC)JExon Deletionmouse

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