Chst2 | carbohydrate sulfotransferase 2

GeneMGI:1891160Synonyms: C130041E03Rik, N-acetylglucosamine-6-O-sulfotransferase, +2 more

Physiological systems

20 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Renal/urinary system

9 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:22Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



enlarged lymph nodes	1 supporting dataset	Chst2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Chst2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
increased circulating aspartate transaminase level	1 supporting dataset	Chst2^em1(IMPC)Mbp	homozygote	Late adult	1.26x10^-5
enlarged lymph nodes	2 supporting datasets	Chst2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
hydrometra	1 supporting dataset	Chst2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Chst2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Chst2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	2 supporting datasets	Chst2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Chst2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Chst2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Chst2.

Associated images

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Histopathology

There is no histopathology data found for Chst2.

IMPC related publications

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External links

No external links available for Chst2.

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*Chst2^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse
*Chst2^{tm466508(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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