Kcne2 | potassium voltage-gated channel, Isk-related subfamily, gene 2

GeneMGI:1891123Synonyms: 2200002I16Rik, MiRP1

Physiological systems

13 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system

11 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

4Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating total protein level	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.16x10^-6
decreased mean corpuscular volume	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.36x10^-5
increased circulating magnesium level	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.49x10^-6
decreased hematocrit	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.46x10^-5
decreased circulating iron level	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.33x10^-9
thrombocytosis	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.42x10^-8
decreased circulating serum albumin level	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.16x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.18x10^-8
decreased circulating bilirubin level	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.41x10^-6
decreased hemoglobin content	1 supporting dataset	Kcne2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.8x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kcne2.

Associated images

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Histopathology

There is no histopathology data found for Kcne2.

IMPC related publications

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External links

No external links available for Kcne2.

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*Kcne2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Kcne2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Kcne2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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