Brwd1 | bromodomain and WD repeat domain containing 1

GeneMGI:1890651Synonyms: D530019K20Rik, G1-403-16, +3 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Hematopoietic system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small testis	1 supporting dataset	Brwd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Brwd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Brwd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Brwd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased circulating cholesterol level	1 supporting dataset	Brwd1^em1(IMPC)Tcp	homozygote	Early adult	2.77x10^-5
female infertility	1 supporting dataset	Brwd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Brwd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased circulating HDL cholesterol level	1 supporting dataset	Brwd1^em1(IMPC)Tcp	homozygote	Early adult	4.88x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Brwd1.

Associated images

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Histopathology

There is no histopathology data found for Brwd1.

IMPC related publications

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External links

No external links available for Brwd1.

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*Brwd1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Brwd1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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