Nek7 | NIMA (never in mitosis gene a)-related expressed kinase 7

GeneMGI:1890645Synonyms: 2810460C19Rik

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging Renal/urinary system

18 No significant impact

3 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

increased urine microalbumin level1 supporting datasetNek7tm1b(EUCOMM)HmguheterozygoteEarly adult8.33x10-9 
preweaning lethality, complete penetrance1 supporting datasetNek7tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nek7tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Nek7tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Nek7tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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